Gan Z, Gangadharan V, Liu S, Körber C, Tan LL, Li H, Oswald MJ, Kang J, Cortecero JM, Männich D, Groh AKuner T, Wieland S, Kuner R. Layer-specific pain relief pathways originating from primary motor cortex, Science. 378:1336-1343, 2022. doi: 10.1126/science.add4391. Epub 2022 Dec 22. PMID: 36548429. Press releases from Heidelberg University Hospital in English and German.

Gangadharan V, Zheng H, Taberner FJ, Landry J, Nees TA, Pistolic J, Agarwal N, Männich D, Benes V, Helmstaedter M, Ommer B, Lechner SG, Kuner T, Kuner RNeuropathic pain caused by miswiring and abnormal end organ targetingNature (2022) Published online: 25 May 2022. Press release in English and German.

Oswald MJ, Han Y, Li H, Marashli S, Oglo DN, Ojha B, Naser PV, Gan Z, Kuner R. Cholinergic basal forebrain nucleus of Meynert regulates chronic pain-like behaviour via modulation of the prelimbic cortex. Nat Commun. 2022 Aug 25;13(1):5014. doi: 10.1038/s41467-022-32558-9.

Tan LL, Oswald MJ, Kuner RNeurobiology of brain oscillations in acute and chronic pain. Trends Neurosci. 2021 Aug;44(8):629-642.  doi: 10.1016/j.tins.2021.05.003.

Tan LL, Kuner RNeocortical circuits in pain and pain relief. Nat Rev Neurosci. 2021 Aug;22(8):458-471. doi: 10.1038/s41583-021-00468-2. Epub 2021 Jun 14. PMID: 34127843.

Gan Z, Li H, Naser PV, Oswald MJ, Kuner R. Suppression of neuropathic pain and comorbidities by recurrent cycles of repetitive transcranial direct current motor cortex stimulation in mice. Sci Rep. 2021 May 6;11(1):9735. doi: 10.1038/s41598-021-89122-6. PMID: 33958647; PMCID: PMC8102487.

Gan Z, Li H, Naser PV, Han Y, Tan LL, Oswald MJ, Kuner RRepetitive non-invasive prefrontal stimulation reverses neuropathic pain via neural remodelling in mice. Prog Neurobiol. 2021 Jun;201:102009. doi: 10.1016/j.pneurobio.2021.102009. Epub 2021 Feb 20. PMID: 33621593.

Finnerup NB, Kuner R, Jensen TS. Neuropathic Pain: From Mechanisms to Treatment. Physiol Rev. 2021 Jan 1;101(1):259-301. doi: 10.1152/physrev.00045.2019. Epub 2020 Jun 25. PMID: 32584191.

Kuner R, Kuner T. Cellular circuits in the brain and their modulation in acute and chronic pain. Physiol Rev. 2020 Jun 11. doi: 10.1152/physrev.00040.2019.

Tan LL,  Oswald MO, Heinl C,  Retana O, Kaushalya S,  Monyer H,  Kuner R. . Gamma oscillations in somatosensory cortex recruit prefrontal and descending serotonergic pathways in aversion and nociception. Nature Communications. 2019 Feb 28;10(1):983. doi: 10.1038/s41467-019-08873-z.

Naser PV and Kuner R. Peripheral Kappa Opioid Receptor Signaling Takes on a Central Role. Neuron 99(6):1102-1104, 2018

Tan LL, Pelzer P, Heinl C, Tang W, Gangadharan VFlor HSprengel RKuner TKuner R. A key role for a mid-cingulate cortex-posterior insula pathway in nociceptive hypersensitivity, Nature Neuroscience, 20(11):1591-1601, 2017

Naser PV, Kuner R. Molecular, cellular and circuit basis of cholinergic modulation of pain. Neuroscience. pii: S0306- 4522(17)30625-5, 2017

Kuner R and Flor H, Structural plasticity and reorganisation in chronic pain, Nature Reviews Neuroscience, 18(1):20-30, 2016

Gangadharan VKuner R. Unravelling spinal circuits of pain and mechanical allodynia. Neuron 87:673-5, 2015

Lu J, Luo C, Bali KK, Xie R-G, Mains RE, Eipper BA, Kuner R. A role for Kalirin-7 in nociceptive sensitisation via activity-dependent modulation of spinal synapses. Nature Communications, 6:6820, 2015

Simonetti M*, Hagenston AM*, Vardeh D*, Freitag E*, Mauceri D*, Lu J, Satagopam VP, Schneider R, Costigan M, Bading HKuner R. Nuclear calcium signaling in spinal neurons drives a genomic program required for persistent inflammatory pain. Neuron77, 43-57, 2013 * equal contributions.


Other publications:

Stegemann A, Liu S, Romero OR, Oswald M, Han Y, Beretta C, Tan L, Wisden W, Gräff J, Kuner R. Prefrontal engrams of long-term fear memory perpetuate pain perception. Preprint on Research Square, 2022, DOI: (currently under revision at Nature Neuroscience).