Postdoc Positions:


Application material:

Interested candidates should submit their application to a specified project including CV, 2 references, and a mission statement explaining how the conceptual and methodological background of the applicant matches the specified project. Candidates can maximally apply for 2 postitions simultaneusly.

How to apply:

Please send the application material to  mentioning the Job ID of the particular position.

Salary:  

Fully-funded Postdoc position as per German regulations (TVL-13)

Contract length:

2-4 years, depending on project.



Postdoc positions available!


Job ID: SFB1158postdoc_RK

Project leader: Rohini Kuner

Email:

Application Deadline:

30 September 2019

Start of the project:

01 January 2020

Project description:

Our laboratory works on elucidating mechanisms and circuits underlying chronic pain (see, for example, Tan et al. Nature Communications 2019; Tan et al. Nature Neuroscience 2017; Vicuna et al. Nature Medicine 2015; Kuner and Flor, Nature Reviews Neuroscience 2016).

We are seeking PhD students or experienced postdoctoral fellows in projects aimed at elucidating brain pathways and mechanisms involved in chronic pain in mouse models. Methods include viral-based circuit mapping, labelling cellular engrams, optogenetics, chemogenetics, in vivo multiphoton imaging, in vivo electrophysiology, neuromodulation and behavior.

One project is focused on understanding circuits mediating analgesia via brain stimulation approaches, such as transcranial magnetic stimulation, using transgenic mice and the above-described methods. Another involves in vivo recordings of brain oscillatory activity and addressing their relevance to pain chronicity. Moreover, projects addressing the cellular basis of specificity for pain versus pain-unrelated functions of the brain are planned.

Applicants must have a strong background and training in neuroscience, preferably at least 2 of the methods described above. Postdoctoral candidates with experience in in vivo imaging or electrophysiology and first author publications are particularly encouraged to apply.

 

Human pluripotent stem cell-derived neurons as a tool to study central and peripheral nociceptive mechanisms


Job ID: SFB1158postdoc_CAG

Project leader: Claudio Acuna Goycolea

Email:

Application Deadline:

31 August 2019

Start of the project:

at the earliest

Project description:

Project description: We are looking for 2 highly-motivated postdoc candidates to work on our recently funded project “human pluripotent stem cell-derived neurons as a tool to study central and peripheral nociceptive mechanisms”. Our project is part of the 2nd funding period of the Heidelberg Pain Consortium SFB1158 .

Deriving human neurons from pluripotent stem cells has become an essential tool to study mechanisms of brain disease, to validate findings in a human-cell background, and to assess efficacy, toxicity and tolerance of newly-developed drugs. Our project aims to develop and use this technology in the context of pain research. We plan to implement and use novel protocols to differentiate multiple types of peripheral and central neuronal and non-neuronal cells essential to study pain, co-culture systems to reconstitute rudimentary networks, and a pipeline for analysis that involves RNAseq, electrophysiology, imaging, and super-resolution microscopy. Experience in one or several of the following areas would be preferred but not necessary:

- Human ESC or iPSC culture techniques

- Patch clamp/calcium imaging

- RNAseq analysis

- CRISPR/gene targeting techniques

- Super-resolution microscopy

Candidates should send their CV, a brief description of their research background & interests and names/contact of referees to:

 

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